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Try using two fingers and if this work then you have enabled a feature called talkback - Settings - Accessibility then Talkback at the top
So in safe mode it is ok?
You may need to perform a system repair but back up all your files first
Switch off your phone and unplug from Pc (Hold volume up and power for around 10 seconds)
Start PC Companion and select Support zone then Update my phone/tablet then in Blue Repair my phone/tablet and follow the onscreen instructions - When prompted connect your phone still switched off holding volume down - This should start the repair or reformat process
If you are using Windows 8/8.1 or a 64bit operating system then adjust the settings for PC Companion and run in compatibility mode and chose Windows 7 or XP